Isaiah described Assyria as the ‘rod of YHWH’s anger’ (Isa 10:5). The Neo-Assyrian Empire was the dominant power during the period of First Isaiah. After discussing the historical, canonical and geopolitical background I will explain the imprint of the Assyrian Empire on the book of Isaiah. I will use 10:5-19 as a case study to demonstrate the impact and adaptation of imperial themes within the book.